M. Mackenny: search on Z-Library

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1

Design and synthesis of morpholine derivatives. SAR for dual serotonin & noradrenaline reuptake inhibition

Paul V. Fish, Christopher Deur, Xinmin Gan, Keri Greene, David Hoople, Malcolm Mackenny, Kimberly S. Para, Keith Reeves, Thomas Ryckmans, Cory Stiff, Alan Stobie, Florian Wakenhut, Gavin A. Whitlock

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 148 KB

english, 2008

2

Designing rapid onset selective serotonin re-uptake inhibitors. Part 3: Site-directed metabolism as a strategy to avoid active circulating metabolites: Structure–activity relationships of (thioalkyl)phenoxy benzylamines

Donald S. Middleton, Mark Andrews, Paul Glossop, Geoffrey Gymer, David Hepworth, Alan Jessiman, Patrick S. Johnson, Malcolm MacKenny, Alan Stobie, Kim Tang, Paul Morgan, Barry Jones

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 297 KB

english, 2008

3

Design and optimization of selective serotonin re-uptake inhibitors with high synthetic accessibility Part 1

Mark Andrews, Alan Brown, Jean-Yves Chiva, David Fradet, David Gordon, Mark Lansdell, Malcolm MacKenny

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 670 KB

english, 2009

4

Designing rapid onset selective serotonin re-uptake inhibitors. Part 1: Structure–activity relationships of substituted (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydro-1-naphthaleneamine

Donald S. Middleton, Mark Andrews, Paul Glossop, Geoffrey Gymer, Alan Jessiman, Patrick S. Johnson, Malcolm MacKenny, Michael J. Pitcher, Tony Rooker, Alan Stobie, Kim Tang, Paul Morgan

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 126 KB

english, 2006

5

Designing rapid onset selective serotonin re-uptake inhibitors. 2: Structure–activity relationships of substituted (aryl)benzylamines

Donald S. Middleton, Mark Andrews, Paul Glossop, Geoffrey Gymer, David Hepworth, Alan Jessiman, Patrick S. Johnson, Malcolm MacKenny, Michael J. Pitcher, Tony Rooker, Alan Stobie, Kim Tang, Paul Morga

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 161 KB

english, 2008

6

Design and optimisation of selective serotonin re-uptake inhibitors with high synthetic accessibility: Part 2

Mark Andrews, Alan Brown, Jean-Yves Chiva, David Fradet, David Gordon, Mark Lansdell, Malcolm MacKenny

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.34 MB

english, 2009

7

Enantioselective synthesis of (R)- and (S)-N-Boc-morpholine-2-carboxylic acids by enzyme-catalyzed kinetic resolution: application to the synthesis of reboxetine analogs

Paul V. Fish, Malcolm Mackenny, Gerwyn Bish, Timothy Buxton, Russell Cave, David Drouard, David Hoople, Alan Jessiman, Duncan Miller, Christelle Pasquinet, Bhairavi Patel, Keith Reeves, Thomas Ryckman

Journal:

Tetrahedron Letters

Year:

2009

Language:

english

File:

PDF, 163 KB

english, 2009

8

ChemInform Abstract: Facile Decarboxylation of Nitrobenzeneacetic Acids as a Convenient Route to Alkylnitrobenzenes.

D. J. BULL, M. J. FRAY, M. C. MACKENNY, K. A. MALLOY

Journal:

Year:

1996

File:

PDF, 29 KB

1996

9

Sulfonamides as selective oestrogen receptor β agonists

Lee R. Roberts, Duncan Armor, Carolyn Barker, Andrew Bent, Kirstin Bess, Alan Brown, David A. Favor, David Ellis, Stephen L. Irving, Malcolm MacKenny, Chris Phillips, Nick Pullen, Adam Stennett, Linda

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

10

Serendipity in drug-discovery: A new series of 2-(benzyloxy)benzamides as TRPM8 antagonists

Brown, Alan, Ellis, David, Favor, David A., Kirkup, Tony, Klute, Wolfgang, MacKenny, Malcolm, McMurray, Gordon, Stennett, Adam

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 1.17 MB

english, 2013

11

Multiple dislocations of the carpometacarpal joints

ONI, O, MACKENNY, R

Journal:

The Journal of Hand Surgery: British & European Volume

Year:

1986

Language:

english

File:

PDF, 824 KB

english, 1986

12

Culture: Transgressing Boundaries || Post-Apartheid Performance Art as a Site of Gender Resistance

Virginia MacKenny

Journal:

Year:

2001

Language:

english

File:

PDF, 550 KB

english, 2001

13

Facile Decarboxylation of Nitrobenzeneacetic Acids as a Convenient Route to Alkylnitrobenzenes

Bull, David J., Fray, M. Jonathan, Mackenny, Malcolm C., Malloy, Kerry A.

Journal:

Year:

1996

File:

PDF, 158 KB

1996

14

Synthetic Studies on a Nonsteroidal Progesterone Metabolite: Regioselective N-Alkylation of an Activated Pyrazole

Bradley, Paul, de Koning, Pieter, Gibson, Karl, Lecouturier, Yann, MacKenny, Malcolm, Morao, Inaki, Poinsard, Cedric, Underwood, Toby

Journal:

Year:

2010

Language:

english

File:

PDF, 165 KB

english, 2010

15

Synthesis of Reboxetine Analogues

P. Fish, M. Mackenny, G. Bish, T. Buxton, R. Cave, D. Drouard, D. Hoople, A. Jessiman, D. Miller, C. Pasquinet, B. Patel, K. Reeves, T. Ryckmans, M. Skerten, F. Wakenhut

Year:

2009

Language:

english

File:

PDF, 75 KB

english, 2009

16

Microbiological evaluation of resection margins of the infected diabetic foot ulcer

Macauley, M., Adams, G., Mackenny, P., Kubelka, I., Scott, E., Buckworth, R., Biddiscombe, C., Aitkins, C., Lake, H., Matthews, V., Ashraff, S., Ashwell, S.

Journal:

Diabetic Medicine

Year:

2020

File:

PDF, 7.85 MB

2020